A Computational study of Cyclin-dependent Kinases 1 (CDK1) butyrolactone I complex and the role of Mg Ion in the active site

Abstract

Cyclin-dependent kinases (CDK)1,2,4,and 6 are the protein kinases that play a pivotal role in the cell cycle regulating of all eukaryotic organisms by phosphorylating proteins needed during the cell division cycle...